Which type of arthritis involves progressive inflammation of joint lining?

Rheumatoid arthritis is characterized by progressive inflammation of the joint lining, known as the synovium. This autoimmune disorder leads to the immune system mistakenly attacking the joint tissues, resulting in swelling, pain, and stiffness. Over time, the inflammation can damage the cartilage and bone within the joint, causing structural changes and loss of function. This progressive nature distinguishes rheumatoid arthritis from other types of arthritis, as it involves systemic effects and can affect multiple joints symmetrically.

In contrast, gout primarily results from the accumulation of uric acid crystals in the joints, leading to acute and episodic inflammation rather than a progressive inflammatory process. Osteoarthritis involves the degeneration of cartilage and does not primarily involve the inflammation of the joint lining; it is mainly characterized by wear and tear on the joints. Septic arthritis is an infection within the joint that causes rapid onset of pain and swelling, but it is typically acute, not progressive in nature.